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Product Composition

Active Ingredients:

Tenofovir Disoproxil Fumarate (300 mg)

Lamivudine (300 mg)

Efavirenz (600 mg)

About Tenolam E Tablet

Product Introduction

Tenolam E Tablet is a combination of two antiretroviral medications. It is primarily prescribed for the treatment of HIV (Human Immunodeficiency Virus) infection and helps in boosting the immunity to fight against HIV, thereby managing or treating AIDS (Acquired Immunodeficiency Syndrome). This medication restricts the growth of HIV in the body, reducing the risk of related complications and improving the lifespan of individuals infected with HIV.

Dosage and Administration

Tenolam E Tablet can be taken with or without food. It is highly recommended to take the medicine regularly at the same time each day for maximum effectiveness. Skipping doses can negatively impact your recovery, so it is essential to complete the entire prescribed course of treatment unless advised otherwise by your doctor.

Common Side Effects

Some common side effects of Tenolam E Tablet may include:

Nausea

Diarrhea

Fatigue

Weakness

Fever

Insomnia

Cough

Depression

These side effects are generally temporary, but if they persist or become severe, you should contact your doctor. This medication can also cause dizziness, so it is advised not to drive or operate machinery until you know how it affects you. Staying hydrated may help alleviate some of these side effects.

Precautions

Before starting treatment with Tenolam E Tablet, it is important to consult your doctor if you are pregnant, breastfeeding, or have any existing health conditions. Your doctor may recommend regular blood tests to monitor kidney and liver function, as well as blood counts.

Important Safety Information

Do not take Tenolam E Tablet if you are allergic to any of its ingredients, including Efavirenz, Lamivudine, or Tenofovir Disoproxil Fumarate.

If you are diagnosed with pancreatitis or are at risk of developing it, you should take this medication with caution.

Regular monitoring of blood counts, bone mineral density, liver, and kidney parameters is advised during treatment.

If you are HIV-positive, avoid breastfeeding and sharing personal items (such as razors or toothbrushes) to reduce the risk of transmission.

Composition of Tenolam E Tablet

Tenolam E Tablet contains three active ingredients:

Efavirenz (a nonnucleoside reverse transcriptase inhibitor, NNRTI)

Lamivudine (a nucleoside reverse transcriptase inhibitor, NRTI)

Tenofovir Disoproxil Fumarate (a nucleotide reverse transcriptase inhibitor, NRTI)

These ingredients work synergistically to block the replication of the HIV virus and manage HIV infections effectively.

Uses of Tenolam E Tablet

Treatment of HIV infections

Therapeutic Effects of Tenolam E Tablet

Tenolam E Tablet works by inhibiting the reverse transcriptase enzyme, which is responsible for producing copies of the DNA of the HIV virus. Both Lamivudine and Tenofovir are nucleoside reverse transcriptase inhibitors (NRTIs), while Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI). These medications block HIV replication and prevent further viral growth.

Drug Interactions

It is important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Certain medications may interact with Tenolam E Tablet and reduce its effectiveness or cause side effects.

Storage Information

Store the tablet at a temperature not exceeding 30°C.

Keep the medicine in its original packaging to protect it from light and excessive moisture.

Keep out of reach of children and pets.

How to Consume Tenolam E Tablet

Tenolam E Tablet is for oral consumption. Your doctor will determine the appropriate dosage and treatment duration based on your condition and other factors. Always follow your doctor's instructions. Do not take an extra dose to compensate for a missed dose.

Safety Advices

Pregnancy: Inform your healthcare professional if you are pregnant or planning to become pregnant. Regular tests may be conducted to monitor your child's development.

Breastfeeding: Breastfeeding is not recommended while taking Tenolam E Tablet due to the potential risk of HIV transmission to the baby.

Lungs: The safety of Tenolam E Tablet for patients with lung conditions is not fully known. Contact your doctor if you have any pre-existing lung diseases.

Liver: Inform your physician about any liver disorders before using Tenolam E Tablet, as it should be used cautiously in patients with liver conditions.

Alcohol: Avoid alcohol while taking Tenolam E Tablet, as it may increase drowsiness or other side effects.

Driving: Do not drive or operate machinery while taking this medication as it may cause dizziness or vision problems.

Quick Tips for Tenolam E Tablet

Tenolam E Tablet is a combination of antiretroviral medicines that can slow or stop the progression of HIV infection.

It may also be used to prevent HIV if started within 72 hours of exposure.

Take it with food to increase absorption.

This medication may cause dizziness or sleepiness. Avoid activities requiring focus until you know how it affects you.

Never skip doses, as this can lead to treatment failure.

Practice safe sex and do not share needles or personal items that may be contaminated with blood or fluids.

Bone weakening may occur with prolonged use. Follow your doctor's advice on exercise and supplements.

Side Effects of Tenolam E Tablet

Serious Side Effects:

Rapid breathing

Drowsiness

Nausea, vomiting, and stomach pain

Severe allergic reactions

Severe mood changes, depression, and suicidal thoughts

Confusion, forgetfulness, seizures, and tremors

Liver toxicity

Kidney damage

Autoimmune disorders

Common Side Effects:

Bloating, flatulence

Headache

Insomnia

Skin reactions

Wheezing, swelling, or lightheadedness

Hair loss

Diarrhea

Bone disorders

Weakness

Anemia

Word of Advice

Always inform your doctor about underlying infections, especially in advanced HIV stages, as new infections or inflammation may occur once treatment begins.

Tenolam E Tablet does not reduce the risk of transmitting HIV to others via sexual contact or blood. Continue using safe practices to prevent transmission.

FAQs

Q 1. What should you not take with Tenolam E Tablet?

It is not recommended to take Tenolam E Tablet alongside other HIV medications. Inform your healthcare provider about any other drugs, vitamins, or supplements you are taking.

Q 2. How should Tenolam E Tablets be stored?

Store Tenolam E Tablets below 30°C in its original container, away from children.

Q 3. What should you do if you miss a dose?

Take a missed dose as soon as you remember, but skip it if the next dose is almost due. Do not double the dose.

Q 4. What laboratory tests are required before starting treatment with Tenolam E?

Tests for HBV infection, serum creatinine, urine glucose, and urine protein will be conducted before beginning treatment.

Q 5. How do you know if you are allergic to Tenolam E Tablet?

Look out for severe rash, swelling of the face or lips, and other signs of an allergic reaction. Contact your healthcare provider if you experience these symptoms.

Fact Box of Tenolam E Tablet

Molecule Name: Efavirenz, Lamivudine, Tenofovir Disoproxil Fumarate

Therapeutic Class: Antiretroviral

Pharmacological Classes:

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)

Indications: Treatment of Human Immunodeficiency Virus (HIV-1) infection

References

Macleods Pharmaceuticals Limited

US Food and Drug Administration

NIH Clinical info

KD Tripathi, Essentials of Medical Pharmacology, 8th Edition, 2019