Imanib 400mg Tablet
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Salt: Imatinib (400mg)
Imanib 400mg Tablet is primarily used to treat several types of cancers. It is most commonly prescribed for blood cancers such as chronic myeloid leukemia and acute lymphocytic leukemia, as well as gastrointestinal stromal tumors. This medicine works by targeting specific proteins that are responsible for the growth and spread of cancer cells.
Imanib 400mg Tablet is also used for treating dermatofibrosarcoma protuberans, a skin tumor, and aggressive systemic mastocytosis, a bone marrow condition. The tablet should be taken with food. It is important to take it at the same time each day for maximum benefit. Continue taking it as prescribed by your doctor, even if you don't feel the effects immediately. Do not stop the medication unless directed by your healthcare provider. The duration of treatment will vary depending on the patient's condition and response.
Important Information
Improper use or an overdose of this medication can lead to serious side effects. It might take several weeks or months to notice improvements in your condition.
Common Side Effects
- Edema (swelling)
- Nausea and vomiting
- Muscle cramps and musculoskeletal pain
- Diarrhea
- Rash
- Fatigue
- Abdominal pain
If you notice unexpected rapid weight gain, contact your doctor immediately. Regular monitoring of blood cell counts and liver function may be advised during the course of treatment.
Precautions
- Pregnancy: Imanib 400mg is unsafe for use during pregnancy as it may harm the fetus. Inform your doctor if you are pregnant or planning to become pregnant. Both men and women should use effective contraception during treatment and for 15 days after stopping the medication.
- Breastfeeding: Not recommended as Imatinib passes into breast milk and may harm your baby.
- Liver Function: This medication is not safe for patients with severe liver disease. Dose adjustments may be needed in such cases.
- Kidney Function: Exercise caution if you have kidney issues. Consult your doctor for more guidance.
How to Use
Take Imanib 400mg Tablet exactly as prescribed by your doctor. Swallow the tablet whole, without chewing, crushing, or breaking it. Take it with food to minimize gastrointestinal irritation.
How It Works
Imanib 400mg Tablet is an anti-cancer medication that inhibits the activity of a protein enzyme called bcr-abl tyrosine kinase. This enzyme plays a key role in the abnormal growth of cancer cells. By blocking this protein, Imanib helps slow or stop the spread of cancer, allowing tumors to shrink and providing symptomatic relief.
Safety Advice
- Alcohol: It is uncertain whether it is safe to consume alcohol while on this medication. Please consult your doctor.
- Driving: Imanib 400mg may cause dizziness, blurred vision, or drowsiness. Avoid driving or operating heavy machinery until you understand how the medication affects you.
Missed Dose
If you miss a dose, skip it and continue with your regular schedule. Do not double the dose to make up for a missed one.
Key Tips for Use
- Always take Imanib with food and a large glass of water to prevent nausea.
- It may cause dizziness or blurred vision. Do not drive until you know how the medication affects you.
- Water retention and swelling are common side effects of Imanib. Notify your doctor if you experience rapid weight gain.
- Do not alter the dosage or stop taking the medication without consulting your healthcare provider.
- Your doctor may perform regular tests to monitor liver function and blood cell counts during treatment.
Serious Side Effects
- Heart failure
- Gastrointestinal disorders
- Hypothyroidism
- Liver failure
- Severe swelling or fluid retention
FAQs
How should I take Imanib 400mg tablet?
Take Imanib 400mg with food and a large glass of water. Follow your doctor’s instructions regarding dosage and timing.
Can Imanib 400mg cause skin issues or sensitivity to sunlight?
Yes, Imanib can make your skin more sensitive to sunlight, leading to rashes, redness, and severe sunburn. Always use sunscreen with high SPF and protective clothing when outdoors.
Can Imanib cause kidney damage?
Long-term use of Imanib may affect kidney function. Your doctor may recommend routine blood tests to monitor kidney health.
When should I take Imanib 400mg?
It is usually taken at the same time every day, with food, to avoid stomach issues.
Does Imanib affect memory or concentration?
Memory issues have been reported in some studies. If you experience difficulty concentrating or memory impairment, consult your doctor immediately.
Fact Box
- Molecule Name: Imatinib
- Therapeutic Class: Antineoplastics
- Pharmacological Class: Tyrosine kinase inhibitor
- Indications: Treat certain types of leukemia and other cancers and blood cell disorders.
References
- Imatinib 400mg film-coated tablets – Summary of Product Characteristics (SmPC) – Medicines.org.uk
- FDA HIGHLIGHTS OF PRESCRIBING INFORMATION
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, pp. 915-936.
