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Tenof EM Tablet

₹ 949.00/-

Active Ingredients:
  • Emtricitabine (200mg)
  • Tenofovir disoproxil fumarate (300mg)
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Tenof EM Tablets combine two active substances, Emtricitabine and Tenofovir disoproxil fumarate. These medications form a part of the standard combination therapy for HIV, known as antiretroviral therapy (ART). This combined drug regimen is primarily used for the effective treatment of HIV-1 infection. When adhered to correctly and consistently, Tenof EM Tablets have shown significant efficacy in both the treatment and prevention of HIV.

Antiviral medications like Tenof EM help delay the progression of AIDS, improving the overall quality of life. This combination therapy is ideal for individuals with high viral loads. Though Tenof EM significantly reduces the risk of viral infection, it is not a cure for HIV, and there are still risks of transmission. It is suitable for both adults and children aged 12 years and older who weigh more than 35 kg.

However, Tenof EM should not be used by individuals who have a known hypersensitivity or severe allergic reaction to Emtricitabine, Tenofovir disoproxil fumarate, or any of its components. It is also not recommended for individuals with severe renal impairment or end-stage renal disease who are not undergoing hemodialysis.

Uses of Tenof EM Tablet
Tenof EM Tablet is used for treating HIV-1 infection.

Therapeutic Effects of Tenof EM Tablet
The therapeutic benefits of Tenof EM Tablet include its use for treating HIV infection and as pre-exposure prophylaxis (PrEP). These medications function by inhibiting HIV replication, reducing viral load, boosting immune function, and slowing the progression of HIV. In individuals already infected with HIV, Tenof EM helps control the virus, maintain a low viral load, and improve overall health outcomes.

Interaction of Tenof EM Tablet with Other Drugs
Always inform your healthcare provider about all other medications you are currently taking, including prescription drugs, over-the-counter medications, vitamin supplements, and herbal products. Some medications may interact with Tenof EM Tablet, potentially reducing its effectiveness or leading to unwanted side effects.

Storage Instructions for Tenof EM Tablet
  • Store at a temperature between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and light.
  • Do not freeze the medication.
  • Keep it in its original packaging.
  • Store in a place inaccessible to children and pets.
  • How to Consume Tenof EM Tablet
  • Follow the dosage, frequency, and duration instructions provided by your healthcare provider. Tenof EM can be taken with or without food, with water. Always stick to the prescribed schedule and consult your doctor before altering the dosage.

Safety Advice for Tenof EM Tablet

Pregnancy:
Consult your healthcare provider if you are pregnant or planning to become pregnant before taking Tenof EM Tablet.

Breastfeeding:
Tenof EM Tablet is excreted into human breast milk, but its risks to infants are not fully established. It’s important to consult a doctor before taking it while breastfeeding.

Lungs:
If you have a history of lung disease or experience respiratory symptoms, consult your healthcare provider before using Tenof EM Tablet.

Liver:
The safety of Tenof EM Tablet in individuals with liver disease may depend on the severity of the condition. Discuss with your doctor if you have liver concerns.

Alcohol:
It’s advised to avoid excessive alcohol consumption while using Tenof EM Tablet as alcohol can interfere with its effectiveness and affect liver function.

Driving:
Some users may experience dizziness, drowsiness, or fatigue while taking Tenof EM Tablet. If these symptoms interfere with your ability to drive safely, avoid operating vehicles or heavy machinery.

Side Effects of Tenof EM Tablet
As with any medication, Tenof EM Tablet may cause side effects, although not everyone will experience them.

Serious Side Effects:
  • Kidney issues or renal toxicity
  • Decreased bone mineral density or bone loss
  • Lactic acidosis (accumulation of lactic acid in the blood)
  • Hepatic steatosis (fat accumulation in the liver)
  • Immune reconstitution syndrome (worsening of pre-existing infections when the immune system strengthens)
  • Common Side Effects:
  • Nausea
  • Diarrhea
  • Headache
  • Fatigue
  • Dizziness
  • Insomnia
  • Rash
Precautions and Advice
It’s essential to be aware of the risks and warnings associated with Tenof EM Tablet. Specifically, if you are pregnant or breastfeeding, it’s important to consult your healthcare provider. The medication should be used with caution in individuals with pre-existing conditions such as liver disease, kidney disease, or bone disorders, as it may worsen these conditions. Regular monitoring is advised for these patients to ensure safe usage.

Always adhere to your healthcare provider’s recommendations and maintain consistent communication with them for optimal health outcomes.

FAQs

Q1: Can Tenof EM Tablet be taken with other antiretroviral medications?
Yes, Tenof EM Tablet is commonly used in combination with other antiretroviral medications as part of a multidrug regimen to treat HIV infection. The exact combination will depend on the patient's individual health profile.

Q2: Can Tenof EM Tablet be safely used by older adults?
Yes, but older adults may require dosage adjustments or additional monitoring due to age-related changes in kidney and liver function.

Q3: Can Tenof EM Tablet be used by individuals with pre-existing bone conditions?
People with bone conditions, such as osteoporosis or osteopenia, should be closely monitored while taking Tenof EM. Discuss any concerns about bone health with your doctor.

Q4: Can Tenof EM Tablet prevent all forms of HIV transmission?
Although Tenof EM Tablet significantly reduces the risk of HIV transmission, it does not offer complete protection. Safe sex practices and other preventive measures should still be followed.

Q5: Can Tenof EM Tablet cause lactic acidosis?
While rare, lactic acidosis is a serious potential side effect of Tenof EM. Contact your doctor immediately if you experience unusual weakness, rapid breathing, nausea, abdominal pain, or muscle pain.

Q6: Are bone health monitoring tests needed?
For long-term use of Tenof EM, your healthcare provider may recommend bone density scans or blood tests to assess bone health.

Q7: Can Tenof EM Tablet be used by individuals with liver or kidney disease?
Individuals with liver or kidney disease should use Tenof EM Tablet with caution. Dose adjustments or alternative treatments may be necessary based on the severity of the condition.

Fact Box
  • Molecule Name: Emtricitabine and Tenofovir disoproxil fumarate
  • Therapeutic Class: Antiviral agents
  • Pharmacological Class: Nucleoside reverse transcriptase inhibitors (NRTIs)
  • Indications: HIV-1 infection
References
  • KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
  • Tillomed Laboratories Limited, Electronic Medicines Compendium (EMC), Revised Apr 2020, EMC 
  • Gilead Sciences, Inc, US Food and Drug Administration, Revised on March 2016, FDA 
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